The 1260 Infinity II Online Sample Manager is an online sampling module that connects the analytical world with the process world. The module provides automated sample analysis via direct injections or retained samples from flow reactors, batch reactors, as well as upstream bioreactors and downstream purification devices.
The Online Sample Manager supports both classical flow-through injection and Agilent Feed Injection, mediating the chromatographic sample diluent incompatibility of challenging process samples. The Online Sample Manager provides automated dilutions of up to 1:1000, retain-sample functionality, and direct analysis of the process samples, as well as automated sample preparation.
Features
- Interfaces the analytical with the process world in process analytical technology (PAT) applications via the easy-to-access external sampling interface, enabling automated process sample analysis via LC applications
- Provides a broad range of sampling and injection volumes from 0.1 to 100 μL for enhanced injection flexibility of process samples
- Enables fast process monitoring of critical process parameters (CPPs) and critical quality attributes (CQAs) via direct injections, providing real-time data for greater control and faster understanding of processes
- Supports automated dilutions (up to 1:1000), reaction quenching, sample preparation, and sample archiving via retain-sample functionality
- Efficient sample handling and logistics: 432 vials (2 mL) can be used for at-line sample analyses or with the online retain-sample functionality
- Hybrid injection technology: Classical flow-through injection for seamless method transfer and Agilent Feed Injection to mediate strong sample diluent effects
